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ea0081p355 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

GLP-1 receptor agonists and erectile dysfunction in diabetic men with and without hypogonadism: a 1- year retrospective observational study

Lisco Giuseppe , Isabella Ramunni Maria , De Pergola Giovanni , Jirillo Emilio , Guastamacchia Edoardo , Triggiani Vincenzo , Angelo Giagulli Vito

Background: Erectile dysfunction affects nearly half of men with type 2 diabetes (T2DM), and one-third of diabetic men have hypogonadism1. As an add-on to TRT in hypogonadal men with T2DM, Liraglutide may improve erectile function2, and dulaglutide decreased the incidence of moderate and severe ED in T2DM3.Study aims: To assess the GLP-1RA effect in T2DM men complaining of ED treated with both liraglutide and dulaglutide ...

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ea0090p61 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

The dual GIP/GLP-1 receptor co-agonist Tirzepatide vs GLP-1 receptor agonists as add-on to basal insulin in uncontrolled type 2 diabetes mellitus: A rapid review of randomized controlled trials and meta-analysis

Lisco Giuseppe , De Tullio Anna , Disoteo Olga , De Geronimo Vincenzo , Piazzolla Giuseppina , De Pergola Giovanni , Angelo Giagulli Vito , Jirillo Emilio , Guastamacchia Edoardo , Sabba Carlo , Triggiani Vincenzo

Tirzepatide, a once-weekly dual co-agonist of Glucose-Dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide 1 (GLP-1) receptors, has been demonstrated to improve glucose control and reduced body weight in different therapeutic approaches. With this rapid review and meta-analysis, we systematically reviewed the efficacy and safety of injectable incretin-based therapy added to basal insulin compared to basal insulin plus background treatments titrated rigorously t...

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Endocrine Abstracts

GLP-1 receptor agonists and erectile dysfunction in diabetic men with and without hypogonadism: a 1- year retrospective observational study

The dual GIP/GLP-1 receptor co-agonist Tirzepatide vs GLP-1 receptor agonists as add-on to basal insulin in uncontrolled type 2 diabetes mellitus: A rapid review of randomized controlled trials and meta-analysis

BiosciAbstracts